CDH6 抗体 (AA 250-450)
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北京 101111
Quick Overview for CDH6 抗体 (AA 250-450) (ABIN7872907)
抗原
See all CDH6 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 250-450
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原理
- Cadherin 6 Antibody / CDH6 / K-Cadherin (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the Cadherin 6 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Cadherin 6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Cadherin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDH6 (K-Cadherin (CDH6))
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别名
- Cadherin 6
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背景
- This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
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UniProt
- P55285
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途径
- Cell-Cell Junction Organization
抗原
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