RNASEH2A 抗体 (AA 25-299)
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Quick Overview for RNASEH2A 抗体 (AA 25-299) (ABIN7872867)
抗原
See all RNASEH2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-299
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原理
- RNase H2 subunit A Antibody / RNASEH2A
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R25-L299) was used as the immunogen for the RNase H2 subunit A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RNase H2 subunit A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RNase H2 subunit A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
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别名
- RNase H2 subunit A
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背景
- Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
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UniProt
- O75792
抗原
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