PDE6B 抗体 (AA 25-237)
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Quick Overview for PDE6B 抗体 (AA 25-237) (ABIN7872851)
抗原
See all PDE6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-237
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原理
- PDE6 beta Antibody / PDE6B
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids K25-Q237) was used as the immunogen for the PDE6 beta antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PDE6 beta antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDE6 beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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别名
- PDE6 beta
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背景
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P35913
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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