SLAMF7 抗体 (AA 249-335)
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北京 101111
Quick Overview for SLAMF7 抗体 (AA 249-335) (ABIN7872815)
抗原
See all SLAMF7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 249-335
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原理
- SLAMF7 Antibody / CS1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 249-335 from the human protein was used as the immunogen for the SLAMF7 antibody.
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亚型
- IgG1, kappa
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anti-SLAM Family Member 7 (SLAMF7) (AA 23-226) antibody
SLAMF7 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5G5A4 unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 51-160) antibodySLAMF7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-296) antibodySLAMF7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 23-226) antibodySLAMF7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) antibodySLAMF7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-296) antibodySLAMF7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-335) antibodySLAMF7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 58-85) antibodySLAMF7 适用: 人 WB 宿主: 兔 Polyclonal RB22341 unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 23-175) antibodySLAMF7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SLAMF7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SLAMF7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SLAMF7 (SLAM Family Member 7 (SLAMF7))
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别名
- SLAMF7
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背景
- CS1, also known as novel Ly9, SLAMF7, 19A24 or CRACC, is a homophilic cell surface receptor. It is a member of the SLAM (signaling lymphocytic activation molecule) family of receptors expressed on natural killer (NK) cells, T cells and stimulated B cells. CS1 contains immunoreceptor tyrosine-based switch motifs in its cytoplasmic domain but, unlike other SLAM receptors, it does not recruit SAP (SLAM-associated protein). In humans, CS1 activates NK cells through an EAT-2-mediated pathway that is SAP-independent. CS1 recruits and associates with EAT-2, a protein closely related to SAP. EAT-2 induces phosphorylation of CS1 which then, upon ligand binding, activates downstream cytotoxicity effectors PLC and PI 3K. In mice, the EAT-2 association with CS1 has an inhibitory effect on the activation of NK cells.
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UniProt
- Q9NQ25
抗原
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