GCLM 抗体 (AA 246-274)
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Quick Overview for GCLM 抗体 (AA 246-274) (ABIN7872786)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 246-274
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原理
- GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 246-274 from the human protein were used as the immunogen for the GCLM antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the GCLM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GCLM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GCLM
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背景
- GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
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UniProt
- P48507
抗原
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