Recombinant LI Cadherin 抗体 (AA 242-418)
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Quick Overview for Recombinant LI Cadherin 抗体 (AA 242-418) (ABIN7872766)
抗原
See all LI Cadherin 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 242-418
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原理
- LI Cadherin Antibody / Cadherin 17 (azide and preservative free)
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纯化方法
- Protein A affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 242-418) from the human protein was used as the immunogen for the LI Cadherin antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the LI Cadherin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the LI Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LI Cadherin
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背景
- It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
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UniProt
- Q12864
抗原
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