LI Cadherin 抗体 (AA 242-418)
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Quick Overview for LI Cadherin 抗体 (AA 242-418) (ABIN7872751)
抗原
See all LI Cadherin 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 242-418
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原理
- Cadherin 17 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 242-418) was used as the immunogen for the Cadherin 17 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Cadherin 17 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cadherin 17 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- LI Cadherin
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别名
- Cadherin 17
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背景
- It recognizes a glycosylated protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
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UniProt
- Q12864
抗原
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