RAGE 抗体 (AA 24-320)
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Quick Overview for RAGE 抗体 (AA 24-320) (ABIN7872683)
抗原
See all RAGE (AGER) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-320
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原理
- Rage Antibody / Ager
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant mouse protein (amino acids Q24-E320) was used as the immunogen for the Rage antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Rage antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Rage antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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别名
- Rage
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背景
- Enables S100 protein binding activity, advanced glycation end-product binding activity, and heparin binding activity. Involved in several processes, including cellular response to amyloid-beta, negative regulation of long-term synaptic potentiation, and positive regulation of cytokine production. Acts upstream of or within several processes, including induction of positive chemotaxis, negative regulation of advanced glycation end-product receptor activity, and positive regulation of macromolecule metabolic process. Located in extracellular space and plasma membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, hemolymphoid system gland, and lung. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), cardiovascular system disease (multiple), cystic fibrosis, kidney failure (multiple), and lupus nephritis. Orthologous to human AGER (advanced glycosylation end-product specific receptor).
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UniProt
- Q62151
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途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
抗原
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