AANAT 抗体 (AA 24-205)
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Quick Overview for AANAT 抗体 (AA 24-205) (ABIN7872672)
抗原
See all AANAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-205
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原理
- Aanat Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant mouse Aanat protein (amino acids C24-C205) was used as the immunogen for the Aanat antibody.
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亚型
- IgG
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anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 141-207) antibody
AANAT 适用: 人, 小鼠, 大鼠, 绵羊 ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 22-235) antibodyAANAT 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 1-207) antibodyAANAT 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 27-54), (N-Term) antibodyAANAT 适用: 人 WB 宿主: 兔 Polyclonal RB23834 unconjugated
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应用备注
- Optimal dilution of the Aanat antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Aanat antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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别名
- Aanat
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背景
- Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternative splicing results in multiple transcript variants.
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UniProt
- O88816
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途径
- Photoperiodism
抗原
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