STS 抗体 (AA 24-193)
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Quick Overview for STS 抗体 (AA 24-193) (ABIN7872671)
抗原
See all STS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-193
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原理
- Asc Antibody / Pycard / Tms1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant mouse protein (amino acids K24-S193) was used as the immunogen for the Asc antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Asc antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Asc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- STS (Steroid Sulfatase (STS))
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别名
- Asc
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背景
- PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene. This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9EPB4
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途径
- Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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