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ATR 抗体 (AA 24-1324)

The 兔 多克隆 anti-ATR antibody is suitable to detect ATR in samples from 人. It has been validated for ELISA 和 IF.
产品编号 ABIN7872663
发货至: 中国
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Quick Overview for ATR 抗体 (AA 24-1324) (ABIN7872663)

抗原

See all ATR 抗体
ATR (ATR serine/threonine kinase (ATR))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATR antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 24-1324

    原理

    ATR Antibody / Ataxia telangiectasia and Rad3-related protein / FRP1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids E24-D1324) was used as the immunogen for the ATR antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ATR antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the ATR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ATR (ATR serine/threonine kinase (ATR))

    别名

    ATR

    背景

    Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

    UniProt

    Q13535

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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