MMS19 抗体 (AA 239-998)
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Quick Overview for MMS19 抗体 (AA 239-998) (ABIN7872659)
抗原
See all MMS19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 239-998
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原理
- MMS19 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (E239-R998) was used as the immunogen for the MMS19 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MMS19 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MMS19 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
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别名
- MMS19
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背景
- MMS19 nucleotide excision repair protein homolog is a protein that in humans is encoded by the MMS19 gene. MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.
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UniProt
- Q96T76
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途径
- Nuclear Hormone Receptor Binding
抗原
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