MPND 抗体 (AA 239-471)
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Quick Overview for MPND 抗体 (AA 239-471) (ABIN7872649)
抗原
See all MPND 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 239-471
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原理
- MPND Antibody / MPN domain-containing protein
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human MPND recombinant protein (Position: R239-S471) was used as the immunogen for the MPND antibody.
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亚型
- IgG
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anti-MPN Domain Containing (MPND) (AA 84-181) antibody
MPND 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-MPN Domain Containing (MPND) (AA 1-471) antibodyMPND 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (N-Term) antibodyMPND 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (Middle Region) antibodyMPND 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (N-Term) antibodyMPND 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (AA 172-221) antibodyMPND 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (AA 179-228) antibodyMPND 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MPN Domain Containing (MPND) (AA 8-36), (N-Term) antibodyMPND 适用: 人 WB 宿主: 兔 Polyclonal RB35930 unconjugated
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应用备注
- Optimal dilution of the MPND antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MPND antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MPND (MPN Domain Containing (MPND))
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别名
- MPND
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背景
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MPND antibody detects MPN domain-containing protein, encoded by the MPND gene. MPN domain-containing protein is a nuclear protein with poorly defined functions but is thought to participate in chromatin regulation, protein interactions, and ubiquitin-like modification processes. MPND antibody provides researchers with a useful reagent to study nuclear function, gene regulation, and protein-protein interaction networks.
MPN domain-containing protein belongs to a family of proteins characterized by the Mpr1-Pad1 N-terminal (MPN) domain, which is present in many regulators of the ubiquitin-proteasome system. Research using MPND antibody has shown that it localizes to the nucleus and may contribute to the organization of transcriptional complexes. While its precise molecular role remains under investigation, its structural domain suggests functions in ubiquitin signaling and protein turnover.
Studies with MPND antibody have demonstrated that the protein interacts with chromatin and associates with regulators of gene expression. These interactions suggest that MPN domain-containing protein modulates transcription indirectly through protein scaffolding or chromatin remodeling. This places MPND at the intersection of nuclear structure and gene regulation.
Dysregulation of MPND expression has been observed in certain cancers. Research using MPND antibody has linked altered expression to tumor progression, possibly through changes in nuclear architecture and transcriptional regulation. These findings indicate that MPN domain-containing protein may function as a modulator of cellular growth and survival pathways.
MPND antibody is commonly applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects expression in cultured cells and tissues, immunohistochemistry identifies nuclear expression patterns, and immunofluorescence highlights nuclear localization. These approaches make MPND antibody valuable for exploratory studies into nuclear biology. -
UniProt
- Q8N594
抗原
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