SPTAN1 抗体 (AA 2351-2475)
Our Local Distributor
北京 101111
Quick Overview for SPTAN1 抗体 (AA 2351-2475) (ABIN7872625)
抗原
See all SPTAN1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 2351-2475
-
原理
- SPTAN1 Antibody / Alpha II Spectrin / Alpha Fodrin / NEAS (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A recombinant human partial protein (amino acids 2351-2475) was used as the immunogen for this SPTAN1 antibody.
-
亚型
- IgG2b, kappa
-
-
-
-
应用备注
- Optimal dilution of the SPTAN1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the SPTAN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
-
别名
- SPTAN1
-
背景
- Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein.
-
UniProt
- Q13813
-
途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
抗原
-