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Recombinant T-Box 1 抗体 (AA 235-435)

The 兔 单克隆 anti-T-Box 1 antibody is suitable to detect T-Box 1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872615
发货至: 中国
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Quick Overview for Recombinant T-Box 1 抗体 (AA 235-435) (ABIN7872615)

抗原

See all T-Box 1 (TBX1) 抗体
T-Box 1 (TBX1)

抗体类型

Recombinant Antibody

适用

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  • 31
  • 29
  • 4
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  • 2
  • 1

宿主

  • 68
  • 2
  • 1

克隆类型

  • 58
  • 13
单克隆

标记

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  • 2
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  • 2
  • 2
  • 1
  • 1
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This T-Box 1 antibody is un-conjugated

应用范围

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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

TBXT-7711R
  • 抗原表位

    • 16
    • 9
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    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 235-435

    原理

    Brachyury Antibody / TBXT / Protein T (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 235-435) from the human protein was used as the immunogen for the Brachyury antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Brachyury antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Brachyury antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    T-Box 1 (TBX1)

    别名

    Brachyury

    背景

    The T-box gene family consists of members that share a unique DNA binding domain. The best characterized T-box (Tbx) gene, brachyury or T, encodes a transcription factor that plays an important role in early vertebrate development. Tbx genes are a family of developmental regulators with more than 20 members recently identified among invertebrates and vertebrates. Mutations in Tbx genes have been found to cause several human diseases. The understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/brachyury protein, which is a transcription activator. The T-domain is a highly conserved DNA-binding motif originally defined in brachyury and characteristic of the Tbx family of transcription factors. The murine brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation, but develop anterior mesoderm.

    UniProt

    O15178

    途径

    Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
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