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EIF4G2 抗体 (AA 23-889)

This 兔 多克隆 antibody specifically detects EIF4G2 in WB, ELISA, IF 和 FACS. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7872557
发货至: 中国
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Quick Overview for EIF4G2 抗体 (AA 23-889) (ABIN7872557)

抗原

See all EIF4G2 抗体
EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 85
  • 3

克隆类型

  • 86
  • 2
多克隆

标记

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  • 5
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This EIF4G2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
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    • 3
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    • 1
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    AA 23-889

    原理

    EIF4G2 Antibody / Eukaryotic translation initiation factor 4 gamma 2 / DAP5

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids R23-Q889) was used as the immunogen for the EIF4G2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the EIF4G2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the EIF4G2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

    别名

    EIF4G2

    背景

    Eukaryotic translation initiation factor 4 gamma 2 (also called p97, NAT1, and DAP-5) is a protein that in humans is encoded by the EIF4G2 gene. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

    UniProt

    P78344
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