ILF2 抗体 (AA 23-356)
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Quick Overview for ILF2 抗体 (AA 23-356) (ABIN7872527)
抗原
See all ILF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-356
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原理
- Zebrafish ILF2 Antibody / Interleukin enhancer-binding factor 2 / NF45
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish NF45/ILF2 recombinant protein (amino acids Y23-K356) was used as the immunogen for the Zebrafish ILF2 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish ILF2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish ILF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))
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别名
- ILF2
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背景
- Interleukin enhancer-binding factor 2, also called 'Nuclear factor of activated T-cells 45 kDa,' is a protein that in humans is encoded by the ILF2 gene. The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.
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UniProt
- Q6NZ06
抗原
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