KLHL12 抗体 (AA 23-327)
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Quick Overview for KLHL12 抗体 (AA 23-327) (ABIN7872525)
抗原
See all KLHL12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-327
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原理
- Zebrafish Klhl12 Antibody / Kelch-like protein 12
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Klhl12 recombinant protein (amino acids R23-V327) was used as the immunogen for the Zebrafish Klhl12 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Klhl12 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Klhl12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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别名
- Klhl12
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背景
- Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.
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UniProt
- Q5U374
抗原
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