Ki-67 抗体 (AA 2293-2478) (Biotin)
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北京 101111
Quick Overview for Ki-67 抗体 (AA 2293-2478) (Biotin) (ABIN7872451)
抗原
See all Ki-67 (MKI67) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2293-2478
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原理
- Ki-67 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 2293-2478 from the human protein was used as the immunogen for the Ki-67 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Ki-67 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Ki-67 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
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- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
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别名
- Ki-67
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背景
- Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
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UniProt
- P46013
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途径
- Glycosaminoglycan Metabolic Process
抗原
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