Ki-67 抗体 (AA 2293-2478)
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Quick Overview for Ki-67 抗体 (AA 2293-2478) (ABIN7872448)
抗原
See all Ki-67 (MKI67) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 2293-2478
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原理
- Ki67 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 2293-2478 was used as the immunogen for the Ki67 antibody.
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亚型
- IgG2b, kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Ki67 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Ki67 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
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别名
- Ki67
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背景
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. [UniProt]
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UniProt
- P46013
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途径
- Glycosaminoglycan Metabolic Process
抗原
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