PA2G4 抗体 (AA 228-255)
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Quick Overview for PA2G4 抗体 (AA 228-255) (ABIN7872417)
抗原
See all PA2G4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 228-255
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原理
- PA2G4 Antibody / EBP1 / ErbB3-binding protein 1
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纯化方法
- Purified
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免疫原
- A portion of amino acids 228-255 from the human protein was used as the immunogen for the PA2G4 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PA2G4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the PA2G4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
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别名
- PA2G4
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背景
- PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. The protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. It is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. It has been implicated in growth inhibition and the induction of differentiation of human cancer cells.
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UniProt
- Q9UQ80
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途径
- Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades
抗原
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