LGI4 抗体 (AA 225-531)
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Quick Overview for LGI4 抗体 (AA 225-531) (ABIN7872402)
抗原
See all LGI4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-531
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原理
- LGI4 Antibody / Leucine-rich repeat LGI family member 4
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids E225-H531) was used as the immunogen for the LGI4 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LGI4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LGI4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
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别名
- LGI4
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背景
- The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.
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UniProt
- Q8N135
抗原
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