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Synaptophysin 抗体 (AA 224-313)

The 小鼠 单克隆 anti-Synaptophysin antibody is suitable to detect Synaptophysin in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872390
发货至: 中国
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Quick Overview for Synaptophysin 抗体 (AA 224-313) (ABIN7872390)

抗原

See all Synaptophysin (SYP) 抗体
Synaptophysin (SYP)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Synaptophysin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SYP-3551
  • 抗原表位

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    AA 224-313

    原理

    Synaptophysin Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human Synaptophysin protein fragment within amino acids 224-313 was used as the immunogen for the Synaptophysin antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Synaptophysin antibody should be determined by the researcher.
    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Synaptophysin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Synaptophysin (SYP)

    别名

    Synaptophysin

    背景

    This monospecific monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

    UniProt

    P08247

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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