TSG101 抗体 (AA 223-257)
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北京 101111
Quick Overview for TSG101 抗体 (AA 223-257) (ABIN7872374)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 223-257
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原理
- TSG101 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E223-K257) was used as the immunogen for the TSG101 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TSG101 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TSG101 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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别名
- TSG101
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背景
- TSG101, known as Tumor susceptibility gene 101, is mapped to 11p15. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. And the protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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UniProt
- Q99816
抗原
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