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L1CAM 抗体 (AA 223-1218)

The 兔 多克隆 anti-L1CAM antibody (ABIN7872373) specifically detects L1CAM in WB, ELISA 和 FACS. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7872373
发货至: 中国
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Quick Overview for L1CAM 抗体 (AA 223-1218) (ABIN7872373)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 223-1218

    原理

    CD171 Antibody / L1CAM / NCAM-L1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids E223-Q1218) was used as the immunogen for the CD171 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CD171 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CD171 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    CD171

    背景

    L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

    UniProt

    P32004

    途径

    Synaptic Membrane
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