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Recombinant ATRX 抗体 (AA 2200-2450)

The 兔 单克隆 anti-ATRX antibody (Clone ATRX-7188R) (ABIN7872352) specifically detects ATRX in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7872352
发货至: 中国
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Quick Overview for Recombinant ATRX 抗体 (AA 2200-2450) (ABIN7872352)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

抗体类型

Recombinant Antibody

适用

  • 86
  • 20
  • 6
  • 3
  • 2
  • 2

宿主

  • 49
  • 39
  • 1

克隆类型

  • 54
  • 35
单克隆

标记

  • 54
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATRX antibody is un-conjugated

应用范围

  • 35
  • 32
  • 27
  • 21
  • 13
  • 13
  • 9
  • 9
  • 4
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

ATRX-7188R
  • 抗原表位

    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2200-2450

    原理

    ATRX Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 2200-2450 from the human protein was used as the immunogen for the ATRX antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the ATRX antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the ATRX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome

    UniProt

    P46100
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