CTSC 抗体 (AA 22-463)
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Quick Overview for CTSC 抗体 (AA 22-463) (ABIN7872325)
抗原
See all CTSC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-463
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原理
- CTSC Antibody / Cathepsin C
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids V22-L463) was used as the immunogen for the CTSC antibody.
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亚型
- IgG
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anti-Cathepsin C (CTSC) antibody
CTSC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-463) antibodyCTSC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (Arg394), (cleaved) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 238-252) antibodyVerified CTSC 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 25-134) antibodyCTSC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (C-Term), (cleaved) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 185-234) antibodyCTSC 适用: 人, 小鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-462) antibodyCTSC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CTSC antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CTSC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CTSC (Cathepsin C (CTSC))
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别名
- CTSC
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背景
- Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. In humans, it is encoded by the CTSC gene. This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
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UniProt
- P53634
抗原
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