YWHAB 抗体 (AA 217-246)
Our Local Distributor
北京 101111
Quick Overview for YWHAB 抗体 (AA 217-246) (ABIN7872246)
抗原
See all YWHAB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 217-246
-
原理
- YWHAB Antibody / 14-3-3 beta/alpha
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 217-246 from the human protein was used as the immunogen for the YWHAB antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the YWHAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the YWHAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- YWHAB (14-3-3 alpha + beta (YWHAB))
-
别名
- YWHAB
-
背景
- YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.
-
UniProt
- P31946
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
-