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FERMT1 抗体 (AA 216-677)

The 小鼠 单克隆 anti-FERMT1 antibody (Clone 4A5-14) (ABIN7872244) specifically detects FERMT1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7872244
发货至: 中国
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Quick Overview for FERMT1 抗体 (AA 216-677) (ABIN7872244)

抗原

See all FERMT1 抗体
FERMT1 (Fermitin Family Member 1 (FERMT1))

适用

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宿主

  • 39
  • 9
小鼠

克隆类型

  • 41
  • 7
单克隆

标记

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This FERMT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4A5-14
  • 抗原表位

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    AA 216-677

    原理

    Kindlin-1 Antibody / KIND1

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 216-677 from the human protein were used as the immunogen for the Kindlin-1 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the Kindlin-1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Kindlin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    FERMT1 (Fermitin Family Member 1 (FERMT1))

    别名

    Kindlin-1

    背景

    Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.

    UniProt

    Q9BQL6
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