FERMT1 抗体 (AA 216-677)
Our Local Distributor
北京 101111
Quick Overview for FERMT1 抗体 (AA 216-677) (ABIN7872243)
抗原
See all FERMT1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 216-677
-
原理
- Kindlin-1 Antibody / KIND1 (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Amino acids 216-677 from the human protein were used as the immunogen for the Kindlin-1 antibody.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal dilution of the Kindlin-1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the Kindlin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- FERMT1 (Fermitin Family Member 1 (FERMT1))
-
别名
- Kindlin-1
-
背景
- Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
-
UniProt
- Q9BQL6
抗原
-