NOX5 抗体 (AA 21-765)
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Quick Overview for NOX5 抗体 (AA 21-765) (ABIN7872181)
抗原
See all NOX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-765
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原理
- NOX5 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids A21-F765) was used as the immunogen for the NOX5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NOX5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NOX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NOX5 (NADPH Oxidase 5 (NOX5))
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别名
- NOX5
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背景
- NOX5 (Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. It is found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, NOX5 was identified as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.
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UniProt
- Q96PH1
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途径
- Proton Transport
抗原
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