Geminin 抗体 (AA 21-196)
Our Local Distributor
北京 101111
Quick Overview for Geminin 抗体 (AA 21-196) (ABIN7872144)
抗原
See all Geminin (GMNN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 21-196
-
原理
- Geminin Antibody / GMNN
-
纯化方法
- Affinity purified
-
免疫原
- An E. coli-derived human protein (amino acids V21-E196) was used as the immunogen for the Geminin antibody.
-
亚型
- IgG
-
-
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) antibody
GMNN 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 1-206) antibodyGMNN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) antibodyGMNN 适用: 人 IHC, IF 宿主: 小鼠 Monoclonal CPTC-GMNN-1 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-142) antibodyGMNN 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) antibodyGMNN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) antibodyGMNN 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) antibodyKD Validated GMNN 适用: 人 WB 宿主: 兔 Monoclonal 25GB3475 unconjugated Recombinant Antibody
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 96-123) antibodyGMNN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20074 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 21-196) antibodyGMNN 适用: 人, 小鼠 WB, IHC, IF, ELISA, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) antibodyGMNN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the Geminin antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Geminin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
-
别名
- Geminin
-
背景
- Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
-
UniProt
- O75496
-
途径
- EGFR Signaling Pathway, DNA Replication
抗原
-
