NHP2 抗体 (AA 21-136)
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Quick Overview for NHP2 抗体 (AA 21-136) (ABIN7872130)
抗原
See all NHP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-136
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原理
- NHP2 Antibody / H/ACA ribonucleoprotein complex subunit 2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E21-Q136) was used as the immunogen for the NHP2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NHP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NHP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NHP2 (NHP2 Ribonucleoprotein (NHP2))
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别名
- NHP2
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背景
- This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9NX24
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途径
- Telomere Maintenance
抗原
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