Apolipoprotein D 抗体 (AA 21-119)
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Quick Overview for Apolipoprotein D 抗体 (AA 21-119) (ABIN7872127)
抗原
See all Apolipoprotein D (APOD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-119
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原理
- APOD Antibody / Apolipoprotein D
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 21-119 from the human protein was used as the immunogen for the APOD antibody.
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亚型
- IgG2c, kappa
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应用备注
- Optimal dilution of the APOD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the APOD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Apolipoprotein D (APOD)
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别名
- APOD
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背景
- Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.
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UniProt
- P05090
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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