C6orf150 抗体 (AA 208-522)
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Quick Overview for C6orf150 抗体 (AA 208-522) (ABIN7872110)
抗原
See all C6orf150 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-522
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原理
- cGAS Antibody / cGAMP Synthase
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids L208-F522) was used as the immunogen for the cGAS antibody.
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亚型
- IgG
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anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 211-395) antibody
C6orf150 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 350-522) antibodyC6orf150 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 208-522) antibodyC6orf150 适用: 人 WB, ELISA, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 1-185) antibodyC6orf150 适用: 人 WB 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 273-303), (Middle Region) antibodyC6orf150 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (Middle Region) antibodyC6orf150 适用: 人, 兔, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 225-407) antibodyC6orf150 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the cGAS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the cGAS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))
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别名
- cGAS
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背景
- CGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13.
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UniProt
- Q8N884
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途径
- Activation of Innate immune Response
抗原
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