SPG20 抗体 (AA 205-631)
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Quick Overview for SPG20 抗体 (AA 205-631) (ABIN7872097)
抗原
See all SPG20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 205-631
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原理
- Spartin Antibody / SPART
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids H205-V631) was used as the immunogen for the Spartin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Spartin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Spartin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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别名
- Spartin
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背景
- Spartin is a protein that in humans is encoded by the SPART gene. This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
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UniProt
- Q8N0X7
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途径
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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