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BTBD9 抗体 (AA 200-400)

The 小鼠 单克隆 anti-BTBD9 antibody (Clone BTBD9-7501) (ABIN7871998) specifically detects BTBD9 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7871998
发货至: 中国
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Quick Overview for BTBD9 抗体 (AA 200-400) (ABIN7871998)

抗原

See all BTBD9 抗体
BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

适用

  • 20
  • 2
  • 1

宿主

  • 12
  • 8
小鼠

克隆类型

  • 15
  • 5
单克隆

标记

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
This BTBD9 antibody is un-conjugated

应用范围

  • 16
  • 10
  • 10
  • 9
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

BTBD9-7501
  • 抗原表位

    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 200-400

    原理

    BTBD9 Antibody / BTB/POZ domain-containing protein 9 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the BTBD9 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the BTBD9 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the BTBD9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

    别名

    BTBD9

    背景

    BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.

    UniProt

    Q96Q07

    途径

    Transition Metal Ion Homeostasis
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