Aquaporin 4 抗体 (AA 200-323)
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Quick Overview for Aquaporin 4 抗体 (AA 200-323) (ABIN7871964)
抗原
See all Aquaporin 4 (AQP4) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 200-323
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原理
- Aquaporin 4 Antibody / AQP4 (azide and preservative free)
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纯化方法
- Protein G affinity
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免疫原
- A human partial recombinant protein (from within amino acids 200-323) was used as the immunogen for the Aquaporin 4 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Aquaporin 4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the Aquaporin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Aquaporin 4 (AQP4)
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别名
- Aquaporin 4
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背景
- In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
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UniProt
- P55087
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途径
- Sensory Perception of Sound
抗原
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