Recombinant Syndecan 1 抗体 (AA 200-300)
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Quick Overview for Recombinant Syndecan 1 抗体 (AA 200-300) (ABIN7871955)
抗原
See all Syndecan 1 (SDC1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-300
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原理
- Recombinant SDC1 Antibody / Syndecan-1 / CD138
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 200-300) of human CD138 protein was used as the immunogen for the recombinant SDC1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant SDC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant SDC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Syndecan 1 (SDC1)
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别名
- SDC1
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背景
- CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.
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UniProt
- P18827
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
抗原
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