TARBP2 抗体 (AA 20-366)
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Quick Overview for TARBP2 抗体 (AA 20-366) (ABIN7871866)
抗原
See all TARBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-366
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原理
- TARBP2 Antibody / TRBP
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E20-K366) was used as the immunogen for the TARBP2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TARBP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TARBP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
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别名
- TARBP2
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背景
- RISC-loading complex subunit TARBP2, also called TRBP and Trans-activation-responsive RNA-binding protein, is a protein that in humans is encoded by the TARBP2 gene. HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
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UniProt
- Q15633
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途径
- Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
抗原
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