LRRC59 抗体 (AA 20-307)
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Quick Overview for LRRC59 抗体 (AA 20-307) (ABIN7871860)
抗原
See all LRRC59 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-307
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原理
- LRRC59 Antibody / Leucine-rich repeat-containing protein 59
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids L20-Q307) was used as the immunogen for the LRRC59 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LRRC59 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LRRC59 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
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别名
- LRRC59
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背景
- Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
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UniProt
- Q96AG4
抗原
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