ERG 抗体 (AA 20-274)
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Quick Overview for ERG 抗体 (AA 20-274) (ABIN7871854)
抗原
See all ERG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-274
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原理
- ERG Antibody / Transcriptional regulator ERG
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids E20-Q274) was used as the immunogen for the ERG antibody.
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亚型
- IgG
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anti-ERG, ETS transcription factor (ERG) antibody
ERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyVerified ERG 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-160) antibodyERG 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-486) antibodyERG 适用: 人 IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ERG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ERG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ERG (ERG, ETS transcription factor (ERG))
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别名
- ERG
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背景
- ERG (ETS-related gene) is an oncogene. ERG is a member of the ETS (erythroblast transformation-specific) family of transcription factors. The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined.
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UniProt
- P11308
抗原
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