L1CAM 抗体 (AA 20-242)
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Quick Overview for L1CAM 抗体 (AA 20-242) (ABIN7871846)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-242
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原理
- NCAM-L1 Antibody / L1CAM / CD171
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids I20-L242) was used as the immunogen for the NCAM-L1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NCAM-L1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NCAM-L1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- NCAM-L1
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背景
- L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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