SELT 抗体 (AA 20-195)
The 兔 多克隆 anti-SELT antibody is suitable to detect SELT in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, FACS, WB, IF 和 IHC (p).
产品编号 ABIN7871841
发货至:
中国
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Quick Overview for SELT 抗体 (AA 20-195) (ABIN7871841)
抗原
See all SELT 抗体
SELT
(Selenoprotein T (SELT))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SELT antibody is un-conjugated
应用范围
ELISA, Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 20-195
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原理
- SELT Antibody / SELENOT
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids S20-S195) was used as the immunogen for the SELT antibody.
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亚型
- IgG
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anti-Selenoprotein T (SELT) (AA 48-75), (N-Term) antibody
SELT 适用: 人 FACS, WB 宿主: 兔 Polyclonal RB24793 unconjugated
anti-Selenoprotein T (SELT) (AA 48-75), (N-Term) antibodySELT 适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SELT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SELT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SELT (Selenoprotein T (SELT))
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别名
- SELT
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背景
- This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Thioredoxin reductase-like selenoprotein T is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif found in several redox active proteins. Studies in mice indicate a crucial role for this gene in the protection of dopaminergic neurons against oxidative stress in Parkinson's disease, and in the control of glucose homeostasis in pancreatic beta-cells. Pseudogenes of this locus have been identified on chromosomes 9 and 5.
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UniProt
- P62341
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途径
- Cell RedoxHomeostasis
抗原
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