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PNN 抗体 (AA 2-241)

The 兔 多克隆 anti-PNN antibody is suitable to detect PNN in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN7871787
发货至: 中国
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Quick Overview for PNN 抗体 (AA 2-241) (ABIN7871787)

抗原

See all PNN 抗体
PNN (Pinin, Desmosome Associated Protein (PNN))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PNN antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 2-241

    原理

    Pinin Antibody / PNN / DRSP

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids A2-L241) was used as the immunogen for the Pinin antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Pinin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Pinin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PNN (Pinin, Desmosome Associated Protein (PNN))

    别名

    Pinin

    背景

    Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75/SRSF4, SRM300/SRRM2, and SRRP130/PNISR. Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.

    UniProt

    Q9H307
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