PNN 抗体 (AA 2-241)
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Quick Overview for PNN 抗体 (AA 2-241) (ABIN7871787)
抗原
See all PNN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-241
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原理
- Pinin Antibody / PNN / DRSP
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids A2-L241) was used as the immunogen for the Pinin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Pinin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Pinin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PNN (Pinin, Desmosome Associated Protein (PNN))
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别名
- Pinin
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背景
- Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75/SRSF4, SRM300/SRRM2, and SRRP130/PNISR. Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.
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UniProt
- Q9H307
抗原
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