EIF1 抗体 (AA 2-106)
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Quick Overview for EIF1 抗体 (AA 2-106) (ABIN7871762)
抗原
See all EIF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-106
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原理
- Eukaryotic translation initiation factor 1 Antibody / EIF1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids S2-D106) was used as the immunogen for the Eukaryotic translation initiation factor 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Eukaryotic translation initiation factor 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Eukaryotic translation initiation factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))
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别名
- Eukaryotic translation initiation factor 1
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背景
- Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. Eukaryotic translation initiation factor 1 (eIF1) is crucial for the scanning process in vitro. During the scanning process, eIF1 is a component of a complex involved in recognition of the initiator codon. Translation is also initiated by the role of eIF1 in regulating the activity of ribosomal subunits 43S, 48S and 40S. eIF1 enables 43S ribosomal complexes to discern between cognate and near-cognate initiation codons, sensing the nucleotide content of initiation codons. It is also a promotor, along with eukar-yotic translation initiation factor 1A (eIF1A), for assembly of 48S ribosomal complexes at the initiation codon of a conventional capped mRNA. In addition, eIF1 and eIF1A, together with eukaryotic translation initiation factor 5 (eIF5), function in the formation of stable 40S ribosomal preinitiation complexes.
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UniProt
- P41567
抗原
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