MYBL1 抗体 (AA 199-752)
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Quick Overview for MYBL1 抗体 (AA 199-752) (ABIN7871757)
抗原
See all MYBL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 199-752
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原理
- Myb-related protein A Antibody / A-Myb / MYBL1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids K199-L752) was used as the immunogen for the Myb-related protein A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Myb-related protein A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Myb-related protein A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MYBL1 (Myb-Like Protein 1 (MYBL1))
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别名
- Myb-related protein A
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背景
- Myb-related protein A is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
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UniProt
- P10243
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途径
- Cell Division Cycle, Chromatin Binding
抗原
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