Recombinant Filaggrin 抗体 (AA 198-288)
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Quick Overview for Recombinant Filaggrin 抗体 (AA 198-288) (ABIN7871749)
抗原
See all Filaggrin (FLG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 198-288
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原理
- Recombinant Filaggrin Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 198-288 was used as the immunogen for the recombinant Filaggrin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the recombinant Filaggrin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Filaggrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Filaggrin (FLG)
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别名
- Filaggrin
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背景
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
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UniProt
- P20930
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途径
- Sensory Perception of Sound, Stem Cell Maintenance
抗原
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