PDIA3 抗体 (AA 192-220)
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Quick Overview for PDIA3 抗体 (AA 192-220) (ABIN7871674)
抗原
See all PDIA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 192-220
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原理
- PDIA3 Antibody / Protein disulfide-isomerase A3 / ERp57
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纯化方法
- Purified
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免疫原
- A portion of amino acids 192-220 from the human protein was used as the immunogen for the PDIA3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PDIA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PDIA3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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别名
- PDIA3
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背景
- PDIA3 is the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
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UniProt
- P30101
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途径
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
抗原
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