Recombinant STING/TMEM173 抗体 (AA 190-290)
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北京 101111
Quick Overview for Recombinant STING/TMEM173 抗体 (AA 190-290) (ABIN7871637)
抗原
See all STING/TMEM173 (TMEM173) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 190-290
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原理
- MITA Antibody / Mediator of IRF3 activation / STING1 / ERIS
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the MITA antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the MITA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MITA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- MITA
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背景
- TMEM173 (transmembrane protein 173), also called MITA (Mediator of IRF3 activation), STING1 and ERIS, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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